Allergic rhinitis patients reported high levels of satisfaction for ZETONNA® (ciclesonide) Nasal Aerosol14
Based on Regimen Attributes Composite satisfaction score
Regimen Attributes Composite score*†14
Methods14
A 2-week, randomized, multi-center, 2-period study in patients ≥ 12 years with PAR
Randomized patients (N=327) received ZETONNA 74 mcg after a 2-week washout period
Patient satisfaction with ZETONNA was evaluated after 2 weeks of treatment, expressed from the Regimen Attributes Composite subscale of the Allergic Rhinitis Treatment Satisfaction and Preference (ARTSP) instrument, a patient-reported outcomes measure
The Regimen Attributes Composite score was a coprimary endpoint comprising the average of the sensory impact and regimen management subscales
Baseline reflects recall of satisfaction with prior prescription nasal spray treatment taken within 6 months of trial entry
*On a scale of 0 to 100, where higher scores reflect higher satisfaction
The 76-item satisfaction scale on the ARTSP has 9 satisfaction subscales, 2 of which comprise the Regimen Attributes Composite Score14,‡
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- Regimen Attributes Composite
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- Sensory impact
- Regimen management
- Interference
- Regimen adaptation
- Role limitation
- Regimen difficulties
- Hassle
- Burden
- Perceived relief
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- Sensory attributes such as running out of the nose and running down the throat, taste, and smell related to the treatment
- Describes issues relating to dosing such as number of sprays and ease of use
- How much allergy symptoms or side effects of the nasal spray interfere with one's daily routine
- Convenience and level of satisfaction with the current treatment
- Interference with social interactions
- Levels of pain, discomfort, and side effects perceived to be associated with the treatment
- Amount of hassle experienced due to treatment regimen
- Degree of burden associated with the treatment
- Level of relief and satisfaction with the treatment
| Regimen Attributes Composite | Sensory impact | Sensory attributes such as running out of the nose and running down the throat, taste, and smell related to the treatment |
| Regimen management | Describes issues relating to dosing such as number of sprays and ease of use | |
| Interference | How much allergy symptoms or side effects of the nasal spray interfere with one's daily routine | |
| Regimen adaptation | Convenience and level of satisfaction with the current treatment | |
| Role limitation | Interference with social interactions | |
| Regimen difficulties | Levels of pain, discomfort, and side effects perceived to be associated with the treatment | |
| Hassle | Amount of hassle experienced due to treatment regimen | |
| Burden | Degree of burden associated with the treatment | |
| Perceived relief | Level of relief and satisfaction with the treatment |
‡After 2 weeks of treatment with ZETONNA, improvement from baseline in satisfaction scores was demonstrated in 8 of 9 ARTSP subscales.
